KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
20
Human Site:
S223
Identified Species:
33.85
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S223
L
V
L
A
E
Y
E
S
D
E
E
K
K
V
A
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S223
L
V
L
A
E
Y
E
S
D
E
E
K
K
V
A
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S204
L
V
L
A
E
Y
E
S
D
E
E
K
K
A
A
Dog
Lupus familis
XP_543872
907
102087
S204
L
V
L
A
E
Y
E
S
D
E
E
K
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S205
I
T
K
I
Y
Y
C
S
R
T
H
S
Q
L
A
Rat
Rattus norvegicus
XP_001070646
845
94905
R194
R
L
V
S
L
G
S
R
Q
S
L
C
V
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S221
L
I
L
A
E
Y
E
S
D
E
E
K
K
N
T
Chicken
Gallus gallus
XP_416375
940
105739
D237
I
L
A
E
Y
E
S
D
E
E
K
K
V
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
S212
V
T
K
I
Y
Y
C
S
R
T
H
S
Q
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
F191
R
Y
R
P
V
Q
I
F
F
C
S
R
T
H
S
Honey Bee
Apis mellifera
XP_001121183
769
88327
L154
L
S
Q
F
I
G
E
L
K
K
S
P
Y
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
K165
L
E
M
Q
S
K
K
K
P
A
K
K
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
P217
D
G
K
V
S
R
D
P
N
N
G
D
R
F
D
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
E311
K
E
T
R
E
L
L
E
K
V
G
M
G
T
A
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
100
93.3
80
N.A.
20
0
N.A.
80
13.3
N.A.
20
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
40
20
N.A.
86.6
46.6
N.A.
40
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
36
0
0
0
0
0
8
0
0
0
22
43
% A
% Cys:
0
0
0
0
0
0
15
0
0
8
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
8
36
0
0
8
8
8
15
% D
% Glu:
0
15
0
8
43
8
43
8
8
43
36
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
8
8
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
15
0
0
0
0
15
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
15
0
0
8
0
% H
% Ile:
15
8
0
15
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
22
0
0
8
8
8
15
8
15
50
29
0
8
% K
% Leu:
50
15
36
0
8
8
8
8
0
0
8
0
0
15
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
0
0
15
0
% N
% Pro:
0
0
0
8
0
0
0
8
8
0
0
8
0
0
8
% P
% Gln:
0
0
8
8
0
8
0
0
8
0
0
0
15
0
0
% Q
% Arg:
15
0
8
8
0
8
0
8
15
0
0
8
8
0
0
% R
% Ser:
0
8
0
8
15
0
15
50
0
8
15
15
0
8
15
% S
% Thr:
0
15
8
0
0
0
0
0
0
15
0
0
8
8
8
% T
% Val:
8
29
8
8
8
0
0
0
0
8
0
0
15
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
22
50
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _